xanthinol nicotinate

Objective: To determine the content of xanthinol nicotinate through charge transfer reaction between xanthi- nol nicotinate and chloranilic acid.

目的:通过尼可占替诺与氯冉酸的荷移反应来测定脑脉康制剂中尼可占替诺的含量。

Determination of Nicorandil Based on Its Polarographic Catalytic Wave;

尼可地尔的极谱催化波法测定

Determination of Nicorandil Based on Cation Surfactant Enhancement by Single Sweep Oscillopolarography;

表面活性剂增敏单扫描示波极谱法测定尼可地尔

Effects of ischemic postconditioning and preconditioning induced by Nicorandil on myocardial ischemia/reperfusion injury in isolated rat heart;

尼可地尔后处理联合预处理对离体心肌缺血/再灌注的作用研究

Role of 5-HT_(2A) receptor in increase in respiratory-related rhythmic discharge activity by nikethamide in neonatal rat transverse medullary slices;

5-HT_(2A)受体在尼可刹米增强新生大鼠延髓脑片呼吸放电中的作用

The effect of nikethamide on rabbit s pupils;

尼可刹米对实验家兔瞳孔的影响

Results Glibenclamide 3mg/kg can induce coronary artery oscil lation,and this phenomenon expressed by thin artery strongly;the oscillation can ’t be restrained by nitroglycerin,but can be terminated by nicorandil.

方法　用优降糖诱发冠状动脉震颤后分别用尼可的尔、硝酸甘油观察两药对震颤的影响。

Objective To investigate the effects of adenosine triphosphate-sensitive potassium (K + ATP ) channel opener nicorandil (Nic), K + ATP inhibitor glibenclamide (Gli) and voltage gated potassium (K + V) channel inhibitor 4-aminopyridine (4-AP) on the morphine (Mor) antinociception during intrathecal administration in rats.

随机每 5只 SD大鼠为一组于术后第 7天经导管蛛网膜下腔分别注射 10 μL下列药物 :K+ ATP通道开放剂尼可的尔 (Nic) 5 μg、K+ ATP通道抑制剂格列本脲 (Gli) 2 μg、K+ V 通道抑制剂 4 -氨基吡啶 (4 - AP)2μg、吗啡 (Mor) 5μg、 Nic 5μg+Mor 5μg、 Gli 2μg+Mor 5μg、 4 - AP 2μg+Mor 5μg或等量盐水 (Sal)。

An improved synthetic route of nicomol was introduced in the thesis.

介绍了合成治疗高脂血症的烟酸类药物尼可莫尔的合成路线 ,本路线采用了一勺烩的方法 ,简化了操作 ,总收率为 5 9%。