Sucrosofate

Studies on the optimal technology factors of extracting sulfated polysaccharides from alga Gracilaria tenuispitata;

细江蓠硫酸酯多糖的提取工艺优化

Research on ultrasonic acid extraction and properties of sulfated polysaccharides from gracilaria tenuistipitata;

超声酸提江蓠硫酸酯多糖工艺及其性质研究

Synthesis of Angelica Sinensis polysaccharide sulfate and their effects on splenocyte proliferation in vitro;

当归多糖硫酸酯的合成及其对脾细胞增殖的作用

Anti-HIV activities of Achyranthes bidentata polysaccharide sulfate in vitro and in vivo;

牛膝多糖硫酸酯体外和体内抗艾滋病病毒作用

Objective:To investigate the effect of chlorosulfonic acids on the synthesis of Angeli- ca polysaccharide sulfate (APS) and assess the APS activities against L6565 murine retrovirus.

目的:对当归多糖进行硫酸酯化修饰,并观察当归多糖硫酸酯(APS)抗小鼠L6565逆转录病毒的作用,以探讨氯磺酸对当归多糖硫酸酯化过程的影响及APS治疗艾滋病的可能性。

AIM: Resercheres are more and more interested in polysaccharide sulphates for its anti-virus effects, especially for its anti-HIV activity.

目的:多糖硫酸酯的抗病毒作用,尤其是抗HIV-1的作用,越来越受到各国学者的广泛关注。

Fifteen target compounds were synthesized with the following three steps: amino acids were protected to form carbobenzoxyamino acid methyl esters, the carbobenzoxyamino acid methyl esters reacted with hydrazine to give carbobenzoxy amino acid hydrazides, and treatment of the carbobenzoxy amino acid hydrazides with glycosyl isothiocyanates afforded 3a～3o in 65%～86% yields.

通过对5种氨基酸酯化和氨基保护得到苄氧羰基氨基酸甲酯,经肼解制备苄氧羰基氨基酸酰肼,然后分别与3种不同的糖基异硫氰酸酯反应,制备了相应的目标化合物15个,且产率均在60%以上。

The reaction of 2 with glycosyl isothiocyanates 3～5 gave the novel compounds, N-glycosyl-N'-amido thioureas 6～8.

以L-α-氨基酸为起始原料,经酯化、氨基保护、肼解制得N-对甲苯磺酰基-L-α-氨基酸酰肼2,再与糖基异硫氰酸酯3～5反应,得到9种新型N-糖基-N'-酰氨基硫脲6～8,然后在Hg(OAc)2/EtOH条件下关环,合成了一系列新的2-对甲苯磺酰氨基烃基-5-糖氨基-1,3,4-噁二唑类化合物9～11。

The glycosyl isothiocyanates 1a～1c reacted with anhydrous hydrazine gave N-glycosyl- N'-aminothioureas 2a～2c, which then reacted further with 6-substituted-3-formylchromones 3a～3d to give a series of new N-glycosyl-N′-6-substitutedchromon-3-ylmethylideneaminothioureas 4a～4d, 5a～5d, 6a～ 6d.

糖基异硫氰酸酯(1a～1c)与无水肼反应,生成糖基氨基硫脲2a～2c,再与6-取代-3-甲酰基色酮3a～3d反应,得到一系列新的N-糖基-N′-(6-取代色酮-3-基-亚甲氨基)硫脲类化合物4a～4d,5a～5d,6a～6d。

The extracting technology of fucoidan from sporophyll powder of sea mustard(Undaria pinnatifida) suringar by enzymatic hydrolysis;

用复合酶酶解—热水浸提法提取裙带菜孢子叶粉岩藻聚糖硫酸酯的工艺研究

Extracting technology of fucoidan from kelp Laminaria japonica by enzymatic hydrolysis;

用复合酶酶解提取海带岩藻聚糖硫酸酯的工艺研究

The Anticoagulant Activity of Fucoidan from Brown Seaweeds;

褐藻中岩藻聚糖硫酸酯抗凝血活性研究

Study on Preparation and Physicochemical Analysis of Sulphated Scallop (Patinopecten yessoensis) Viscus Polysaccharides

虾夷扇贝脏器硫酸酯多糖的制备及性质研究

Study on Synthesis Methods of Ginseng Sulfated Polysaccharides and Multiresidue Analysis Methods of Organochlorine Pesticide;

人参硫酸酯多糖的合成方法及其有机氯多残留的分析方法研究

Determination of SO_4~(2-) content of polysaccharides sulfate from rhodiola saohalinensis A.Bor by Ion-chromatography

离子色谱法测定高山红景天多糖硫酸酯中硫酸根含量的研究

Effect of Fucoidan on the Human Renal Interstitial Fibroblast;

褐藻多糖硫酸酯对人肾间质成纤维细胞的影响

Anti-AIDS Effect and Its Machenism of Angelica Polysaccharide Sulphate;

当归多糖硫酸酯抗艾滋病作用及其机制的研究

Preparation and the Structure-Activity-Relationship Study of Sulfated Salvia Polysaccharide;

鼠尾草多糖硫酸酯的制备及抗HIV活性研究

Effects of FPS on Platelet Aggregation and Thrombus Formation;

褐藻多糖硫酸酯影响血小板聚集及血栓形成

Study on Structural Feature, Antitumor Activity of Rice Bran Polysaccharide and Their Sulfates

米糠多糖及其硫酸酯的结构、抗肿瘤活性的研究

Preparation of Injection Fucoidan and Research on Its Physical and Chemical Properties

注射用褐藻多糖硫酸酯的制备及理化性质研究

Progress in Sulfated Polysaccharides Biological Activity and Structure-activity Relationship

硫酸酯化多糖生物活性及其构效关系研究进展

Preparation and Sulfation of Polysaccharides from Pumpkin

南瓜水溶性多糖的制备及硫酸酯化初步研究

Structural Analysis on Preparation of LAMS from Laminarin by ~(13) C NMR

核磁共振碳谱对昆布多糖硫酸酯的结构分析

Study on the relationship of sulfation and structural stability of polysaccharides from pumpkin pulp

南瓜多糖硫酸酯化修饰与结构稳定性关系研究

Physical and chemical characteristics of silk fibroin/fucoidan composite films

丝素/褐藻多糖硫酸酯复合膜的理化性质(英文)

Structure and Conformation Analysis of Sulfated Polysaccharide from the Fruiting Bodies of Hericium erinaceus

硫酸酯化猴头菌多糖的结构与构象分析

Anti-Hyperlycemic Effect of Auricularia Polysaccharides AAP3-1 and Its Sulfated Product SAAP;

黑木耳多糖AAP3-1和硫酸酯化产物SAAP的降血糖功能研究

Studies on Conditions of Xylan Sulfation and the Anticoagulant Activity of Sulfated Xylan;

木聚糖硫酸酯化条件及木聚糖硫酸酯抗凝血活性研究

Conclusion: The technology provide basis for industry production.

结论:该工艺为多糖硫酸酯工业化生产提供了依据。