Roxadimate

Objective: To synthesize roxatidine acetate and its salt; to design and synthesize phenoxypropylamines and observe their effect on the inhibition of gastric juice acid.

目的:合成H_2受体阻滞剂罗沙替丁乙酸酯盐酸盐;设计合成具有抑酸活性的苯氧丙胺类化合物,并考察其体外抑酸活性。

The pharmacological peculiarity of the fourth histamine H_2-Receptor antagonists(Roxatidine acetate) is described in much detail.

本文系统地介绍了消化性溃疡的发病机理以及H_2-受体拮抗剂在消化性溃疡中的治疗作用，详细地阐述了第四代H_2-受体拮抗剂罗沙替丁乙酸酯(Roxatidine Acetate)的药理作用和特点，对罗沙替丁乙酸酯的合成工艺进行了考察，确定了较好的反应条件，得到了罗沙替丁乙酸酯的盐酸盐，四步反应总收率为29％，产品结构经波谱测试，结果与文献值一致，确证了其结构。

Monitoring the Synthesis of Derivatives of Roxatidine Acetate by TLC;

薄层色谱法监测罗沙替丁醋酸酯衍生物的合成

Roxatidine acetate is usually obtained from 3-hydroxybenzaldehyde by chemosynthesis.

目的罗沙替丁醋酸酯是以间羟基苯甲醛为原料进行生产的具有优良的抗消化性溃疡活性的化学合成药物。

OBJECTIVE To study the effects of butylamine roxatidine acetas(BRA) on experimental gastric ulcer in mice.

目的研究正丁胺基罗沙替丁乙酸酯(BRA)对动物实验性胃溃疡的影响。

Effect of Butylamine Roxatidine Acetas on gastric juice excretion in rats with gastric ulcer

正丁胺基罗沙替丁乙酸酯对胃溃疡大鼠胃液分泌的影响

Synthesis and Inhibition of Gastric Juice Acid of Roxatidine Acetate and Its Analogues;

罗沙替丁乙酸酯及其类似物的合成与抑酸活性研究

Synthesis and characterization of the derivatives of roxatidine and study of activity

罗沙替丁乙酸酯衍生物的合成和抗溃疡活性的研究

The Mechanism of Affecting Ulcer Healing of Butylamine Roxatidine Acetate in Gastric Ulcer Rats Indued by Acetic Acid

正丁胺基罗沙替丁乙酸酯影响乙酸诱发胃溃疡大鼠溃疡愈合作用机制研究

Effect of Butylamine Roxatidine Acetas on Experimental Gastric Ulcer and Its Acute Toxicity

正丁胺罗沙替丁乙酸酯对动物实验性胃溃疡及急性毒性实验的影响

Investigation on the pharmacokinetics of iv gtt single and multi-dose roxatidine acetate hydrochloride injection in healthy volunteers

注射用盐酸罗沙替丁醋酸酯健康人体的药动学

Selecting Developing Agent in Synthesis Process of Roxatidine Acetate by TLC

罗沙替丁醋酸酯合成的薄层色谱展开剂的选择

Influence of butylamine roxatidine acetate on seroactive fractions in rats with gastric ulcer

正丁胺基罗沙替丁乙酸脂对胃溃疡大鼠胃黏膜活性因子的影响

ethyl ionylidene acetate

乙酸乙基紫罗兰叉酯

polyethylene glycol fumarate

聚反丁烯二酸乙二醇酯

dimercaptoethyl maleate

顺丁烯二酸二巯基乙酯

dibutoxy ethyl sebacate

癸二酸二丁氧基乙酯

diethyl butylmalonate

正丁基丙二酸二乙酯

n-Butyl acetate for industrial use

GB/T3729-1991工业乙酸丁酯

ethylene-butyl acrylate copolymer

乙烯-丙烯酸丁酯共聚物

ethyl-t-butyl peroxyoxalate

过氧草酸乙基特丁酯

butyl acetoxystearate

乙酰氧基硬脂酸丁酯

acetyltributyl citrate

柠檬酸乙酰三丁基酯