Pegaspargase

Extract L-Asparaginase by column chromatography;

柱层析法提取门冬酰胺酶

The crude L-asparaginase was purified by ion exchange chromatography of DEAE-Sephadex A-50.

采用 DEAE- Sephadex A- 5 0层析纯化门冬酰胺酶 ,HPL C检测结果表明 ,产品纯度和收率均有提

Hyperglycemia induced by asparaginase and dexamethasone:2 case reports;

门冬酰胺酶合用地塞米松致高血糖2例

Cerebrospinal fluid asparagine concentrations after high-dose of L-asparaginase in childhood with acute lymphoblastic leukemia;

急性淋巴细胞白血病患儿大剂量静脉滴注门冬酰胺酶治疗后脑脊液门冬酰胺浓度

Methods :Gene fragments encoding a truncated asparaginasefragment mutant,native C-peptide,a hinge fragment of human IgG1,an extra acid-labile dipeptide and a basic-amino-acid-riched octopeptide were introduced in turn into plasmid pET28a.

方法:将编码截短的门冬酰胺酶突变体(ansB-C),天然C肽,人IgG1铰链区(hinge),额外的酸敏感二肽(DP)以及富含碱性氨基酸的8肽(KRKRKKSR)的核苷酸序列依次分别插入pET28a载体中,构建表达载体pEDCC。

Construction and Enzyme-activity Assessment of L-Asparaginase Mutants;

L-门冬酰胺酶突变体的构建及其活性测定(英文)

Effects of recombinant L-asparaginase proliposomes on the growth of HL-60 cells;

重组L-门冬酰胺酶前体脂质体对HL-60细胞生长的影响

Combination of large dose of methotrexate and L-asparaginase in treatment of adult patients with refractory or recurrent acute lymphoblastic leukemia;

大剂量甲氨蝶呤联合L-门冬酰胺酶治疗成人难治或复发急性淋巴细胞白血病

Studies on Immobilized L-asparaginase Based on Polyacrylamide and PEG;

聚丙烯酰胺-聚乙二醇对L-天门冬酰胺酶的包埋研究

Effect of β-cyclodextrin on the stability of L-asparaginase;

β-环糊精对L-天门冬酰胺酶的稳定作用

The research advance on reducing adverse effects of L-asparaginase;

降低L-天门冬酰胺酶毒副作用的研究进展

Soluble and functional expression of L asparaginase in Escherichia coli;

L-天门冬酰胺酶的可溶性表达研究

A combination of guanidine HCl and Triton X 100 can release L asparaginase (EC 3.

研究了用盐酸胍和TritonX 10 0处理ATCCEscherichiacoli 1130 3细胞 ,使细胞内的L-天门冬酰胺酶 (EC 3。

coli L asparaginase was modified by N,O carboxymethyl chitosan.

采用水溶性壳聚糖对 L-天门冬酰胺酶进行化学修饰 ,修饰后的酶活回收率高达 70 % ,修饰酶的比活为每毫克蛋白质 1 2 1 。

Studies on Immobilized L-asparaginase Based on Polyacrylamide/N,N'-methylenebisacrylamide;

聚丙烯酰胺/N,N'-亚甲基双丙烯酰胺固定化L-天门冬酰胺酶的研究

Side effects of L-asparaginase in different administrating use.

左旋门冬酰胺酶不同用法副作用的观察

Nursing care of a patient with severe acute pancreatitis induced by L-asparaginase

1例左旋门冬酰胺酶诱发重症急性胰腺炎病人的护理

Adverse Reaction of Childhood Patients With Malignant Tumor Treated by L-asparaginase

左旋门冬酰胺酶治疗小儿恶性肿瘤毒副反应的观察

Preventing the adverse effect of L-asparaginase during the chemotherapy in children with malignant tumors

左旋门冬酰胺酶治疗儿童恶性肿瘤的毒副作用及其防治研究

Studies on the Preparation, Purification and Identification of N-terminal Site-Specific Mono-PEGylation of L-Asparaginase;

N-端聚乙二醇化L-门冬酰胺酶的制备、纯化及鉴定研究

Adverse Influense of Glycometabolism Caused by L-asParaginase in Children Used In Acute LymPhoblastic Leukemia

儿童淋巴细胞白血病应用左旋门冬酰胺酶对糖代谢的影响

Objective To investigate care of the patients with acute leukemia who had complication of central nerve system because of administration of L-ASP.

目的 :探讨急性白血病病人应用左旋门冬酰胺酶后出现中枢神经系统并发症的护理方法。

THE TOXICITY OF L-ASPARAGINASE TO PANCREAS IN TREATING CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

左旋门冬酰胺酶治疗儿童急性淋巴细胞性白血病的胰腺毒副作用观察

Side Effects of L-asparaginase during Therapies for Remission Induction and Maintenance in Children with Acute Lymphocytic Leukemia

儿童急性淋巴细胞白血病诱导缓解及维持期治疗中左旋门冬酰胺酶副作用的比较

The amide nitrogen of glutamine or asparagine functions more effectively than ammonia.

谷酰胺或天门冬酰胺的酰胺氮作用较氨更有效。

Aspartate is readily converted to asparagine.

天门冬氨酸易于转变成天门冬酰胺。

Cyanide can serve as precursor for the amide nitrogen of asparagine.

氰化物可以作一个天门冬酰胺的酰胺氮前体。

Recent Advances in Clinical Studies on PEG-L-asparaginase

PEG-L-天冬酰胺酶的临床研究近况

Studies on the Silk Sericin Protein as a Support of Immobilized L-asparaginase;

以丝胶蛋白为载体的固定化L-天冬酰胺酶研究

Cell Culture and the Fermentation System of Asparagus;

石刁柏细胞培养及其L-天冬酰胺酶发酵

Preparation and Identification of Anti-ASNS Monoclonal Antibody;

抗人天冬酰胺合成酶单克隆抗体的制备与鉴定

Construction and Application of Screening Model of Asparagine Synthetase B in Vitro

天冬酰胺合成酶B体外筛选模型的构建与应用